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ea0081p340 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

Excellent disease control in Berardinelli Seip type 1 patient through dietary therapy alone: only an exception?

Cecchetti Carolina , Belardinelli Elisabetta , Dionese Paola , Teglia Rita , Di Cintio Ilaria , D'apice Maria Rosaria , Pagotto Uberto , Gambineri Alessandra

Background and Objective: Severe metabolic complications generally manifest at an early age in Berardinelli Seip congenital lipodystrophy (BSCL) and their management is especially challenging, often requiring prompt pharmacological treatment with insulin-sensitizers, lipid lowering drugs, insulin and eventually metreleptin. Nutritional intervention with low lipid personalized diets is considered by experts a fundamental tool in handling the disease when associated with ...

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ea0093oc47 | Oral communication 7: Diabetes, Obesity and Metabolism | EYES2023

Amino acids and biogenic amines circadian fluctuation in health and in hypercortisolism states

Galante Greta , Tucci Lorenzo , Improta Ilaria , Bissi Valentina , Perrone Alessandro , Coscia Kimberly , Colombin Giacomo , Di Cintio Ilaria , Vicennati Valentina , Pagotto Uberto , Di Dalmazi Guido , Fanelli Flaminia

Background: Chronic hypercortisolism exhibits irregular circadian rhythm and deranged protein metabolism. Altered amino acid(AA) and biogenic amine(BA) circulating levels were found in patients with hypercortisolism. However, there is limited information about the physiologic circadian fluctuation of AA and BA levels, and it is not known whether this is affected by states of hypercortisolism.Aim: To characterize levels and daily fluctuations of AA and BA...

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Endocrine Abstracts

Excellent disease control in Berardinelli Seip type 1 patient through dietary therapy alone: only an exception?

Amino acids and biogenic amines circadian fluctuation in health and in hypercortisolism states

BiosciAbstracts